Glycerooxazaphospholanes in the synthesis of phospholipid derivatives

Authors
Suvorkin, SV Predvoditelev, DA Nifant'ev, EE
Citation
Sv. Suvorkin et al., Glycerooxazaphospholanes in the synthesis of phospholipid derivatives, RUSS J ORG, 36(5), 2000, pp. 657-662
Citations number
9
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
36
Issue
5
Year of publication
2000
Pages
657 - 662
Database
ISI
SICI code
1070-4280(200005)36:5<657:GITSOP>2.0.ZU;2-5
Abstract
A simple procedure was developed for the synthesis of previously unknown ph ospholipids, including those containing a cationic moiety. These phospholip ids are glycerol esters derived from alkylphosphonamidic aicd. The procedur e is based on the alkylation of accessible 1,3,2-oxazaphospholanes accordin g to Arbuzov, followed by aminolysis of intermediate N-(2-haloethyl)alkylph osphonamidates.