Crinatusins, bioactive Diels-Alder adducts from Cyathocalyx crinatus

Authors
Shibata, K Tatsukawa, A Umeoka, K Lee, HS Ochi, M
Citation
K. Shibata et al., Crinatusins, bioactive Diels-Alder adducts from Cyathocalyx crinatus, TETRAHEDRON, 56(45), 2000, pp. 8821-8824
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
45
Year of publication
2000
Pages
8821 - 8824
Database
ISI
SICI code
0040-4020(20001103)56:45<8821:CBDAFC>2.0.ZU;2-U
Abstract
From the stems of Cyathocalyx crinatus, a rain forest plant in Borneo, six new Diels-Alder adducts, named crinatusins A(1), A(2), B-1, B-2, C-1, and C -2, together with a known chalcone derivative, 4',6'-dihydroxy-3',5'-dimeth yl-2'-methoxychalcone have been obtained. Their structures were determined on the basis of spectroscopic data and chemical methods. Crinatusins showed a lethal toxicity against brine shrimp. (C) 2000 Elsevier Science Ltd. All rights reserved.