The synthesis of C-2-symmetric and axially chiral compounds for recognition and catalysis

Authors
Clews, J Curtis, ADM Malkin, H
Citation
J. Clews et al., The synthesis of C-2-symmetric and axially chiral compounds for recognition and catalysis, TETRAHEDRON, 56(44), 2000, pp. 8735-8746
Citations number
25
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
44
Year of publication
2000
Pages
8735 - 8746
Database
ISI
SICI code
0040-4020(20001027)56:44<8735:TSOCAA>2.0.ZU;2-G
Abstract
Axially chiral amidines and guanidines. some possessing C-2-symmetry, have been targeted as potential chiral catalysts for reactions of alpha,beta -un saturated carboxylic acids or esters. The key step in each synthesis requir ed the coupling of two sterically demanding aromatic compounds to form atro pisomeric biaryl species. (C) 2000 Elsevier Science Ltd. All rights reserve d.