Random-array letter cancellation tasks are commonly used in the clinical as
sessment of visuospatial function. How stimulus properties and aging affect
cancellation performance is not well understood. This study evaluated the
effects of stimulus factors and age on 3 measures of cancellation performan
ce. Thirty younger and 30 older adults each completed 12 cancellation forms
that varied in paper size, stimulus density, and target-to-distractor (T/D
) ratio. Interactions between stimulus factors were identified for a calcul
ated composite measure of speed and accuracy (effectiveness), a standardize
d measure of the time required for completion of forms, and a standardized
measure of the number of omission errors. The results showed complex intera
ctions between stimulus factors that were different for each dependent vari
able. These interactions were generally similar for both age groups. The fi
ndings indicate that both stimulus properties and dependent variables must
be carefully considered in the design and interpretation of cancellation pa
radigms.