Nonsteroidal antiallergic treatments in allergic rhinitis

Allergic rhinitis is characterized by an inflammatory reaction consequent t o an initial IgE-dependent mast cell activation. The conventional treatment is mainly based on antihistamine and topical corticosteroid prescriptions. In this article the authors consider the antiallergic-antiinflammatory act ivity exerted by some nonsteroidal drugs or immunologic treatments. Clinica l and experimental evidence demonstrates that these treatments are able to control allergic inflammation in patients with allergic rhinitis. In conclu sion, treatment of allergic rhinitis may also be based on the prescription of nonsteroidal drugs with antiallergic activity.