Thromboelastography identifies sex-related differences in coagulation

Thromboelastography is an in vitro, point-of-care monitor of whole blood co agulation. Thromboelastography studies have demonstrated a hypercoagulable state during pregnancy. Perhaps the hypercoagulability is attributable to f emale sex hormones. The aim of the study was to determine if sex, in additi on to pregnancy, affected thromboelastography variables by studying male an d female (pregnant and nonpregnant) volunteers. Thromboelastography showed significant (P<0.01) differences in sex, with a significant (P<0.0001) tren d of increasing whole blood coagulability from men through nonpregnant to p regnant women. The thromboelastograph, used as a diagnostic tool, shows tha t women have more whole blood coagulability than men.