Thromboelastography identifies sex-related differences in coagulation

Citation
Hj. Gorton et al., Thromboelastography identifies sex-related differences in coagulation, ANESTH ANAL, 91(5), 2000, pp. 1279-1281
Citations number
6
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
ANESTHESIA AND ANALGESIA
ISSN journal
00032999 → ACNP
Volume
91
Issue
5
Year of publication
2000
Pages
1279 - 1281
Database
ISI
SICI code
0003-2999(200011)91:5<1279:TISDIC>2.0.ZU;2-F
Abstract
Thromboelastography is an in vitro, point-of-care monitor of whole blood co agulation. Thromboelastography studies have demonstrated a hypercoagulable state during pregnancy. Perhaps the hypercoagulability is attributable to f emale sex hormones. The aim of the study was to determine if sex, in additi on to pregnancy, affected thromboelastography variables by studying male an d female (pregnant and nonpregnant) volunteers. Thromboelastography showed significant (P<0.01) differences in sex, with a significant (P<0.0001) tren d of increasing whole blood coagulability from men through nonpregnant to p regnant women. The thromboelastograph, used as a diagnostic tool, shows tha t women have more whole blood coagulability than men.