Sweet's syndrome is a neutrophilic dermatosis characterized clinically by r
aised, erythematous, tender lesions on the face, neck, upper thorax and ext
remities. Several diseases have been associated with this entity. We report
a case of Sweet's syndrome associated with chronic myelogenous leukemia: a
48-year-old woman who developed recurrent skin lesions 3 years after the d
iagnosis of chronic myelogenous leukemia. Progression to an accelerated pha
se of the disease was detected 3 months after the beginning of the skin les
ions. This case shows the convenience of evaluation and closer follow-up of
patients with chronic myelogenous leukemia who develop skin lesions, espec
ially if these lesions are recurrent.