The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 in two crystal forms at 2.2 and 2.9 angstrom resolution

Authors
Fokin, AV Afonin, PV Mikhailova, IY Tsygannik, IN Mareeva, TY Nesmeyanov, VA Pangborn, W Lee, N Duax, W Ciszak, E Pletnev, VZ
Citation
Av. Fokin et al., The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 in two crystal forms at 2.2 and 2.9 angstrom resolution, BIOORG KHIM, 26(8), 2000, pp. 571-578
Citations number
23
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANICHESKAYA KHIMIYA
ISSN journal
01323423 → ACNP
Volume
26
Issue
8
Year of publication
2000
Pages
571 - 578
Database
ISI
SICI code
0132-3423(200008)26:8<571:TTSOTA>2.0.ZU;2-G
Abstract
The three-dimensional structure of the antigen-binding fragment of a monocl onal antibody to human interleukin-2 was determined in two crystal forms by the X-ray method of molecular replacement at 2.2 and 2.9 Angstrom resoluti ons. The spatial structure of the protein and the stereochemistry of its an tigen-binding site were analyzed.