Migraine attacks and sleep in children

Falling asleep as a means of ending migraine attack was studied in 133 4-16 -year-old children in out-patient settings. Children registered 999 migrain e attacks in headache diaries using a visual analogue scale (VAS) in 409 at tacks and a five-face scale in 590 attacks. The distribution of maximal pai n intensity was similar on both scales; on VAS 88% assigned grades between 63 and 100, and on the face scale 93% assigned grades of 4 or 5. Children f ell asleep during 33% of the attacks (n = 329), in 64% of these within the first hour (n = 209). Of the children, 68% (n = 91) had fallen asleep at le ast once during an attack. Falling asleep was more common in children under 8 years of age than in older children. In those under 8 years, 62% (95% co nfidence interval (CI) 49-75%) of attacks were resolved by sleep, in those aged 8-12 years 34% (26-41%), and in children > 12 years 24% (15-33%) (ANOV A, P < 0.0001). Pain was relieved without sleep in 43% (n = 431) of attacks , in 38% of these (n = 383) within the first 4 h. The data on migraine reso lution were missing for 24% (n = 239) of the attacks, most often because th e attack exceeded the 5-h observation period. This study confirms that migr aine attacks in children are extremely painful and often resolve during an interval of sleep in children under 8 years of age.