H. Takechi et al., Screening search for organic fluorophores: Syntheses and fluorescence properties of 3-azolyl-7-diethylaminocoumarin derivatives, CHEM PHARM, 48(11), 2000, pp. 1702-1710
In order to find a highly sensitive fluorophore, 3-azolyl-7-diethylaminocou
marin derivatives were synthesized. Both the absorption and fluorescence ma
xima of the coumarin-thiazole compounds showed red shifts with increases of
the molar absorptivities and fluorescence intensities, in comparison with
those of the corresponding coumarin-oxazole compounds. Among them, 3-(5-eth
oxycarbonyl-1,3-thiazol-2-yl)-7-diethylamino-2H-chromen-2-one (3e) was one
of the most promising candidates as a fluorophore accessible for analytical
purposes in the fields of analytical and biological chemistry.