An alternative base-pairing of catechol-bearing nucleosides by borate formation

Authors
Cao, H Tanaka, K Shionoya, M
Citation
H. Cao et al., An alternative base-pairing of catechol-bearing nucleosides by borate formation, CHEM PHARM, 48(11), 2000, pp. 1745-1748
Citations number
8
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363 → ACNP
Volume
48
Issue
11
Year of publication
2000
Pages
1745 - 1748
Database
ISI
SICI code
0009-2363(200011)48:11<1745:AABOCN>2.0.ZU;2-4
Abstract
A chelator-type beta -C-nucleoside having a catechol ligand as the nucleoba se was found to form a stable 2:1 complex with trimethyl berate, which,vas characterized by H-1-NMR and electrospray ionization time-of-flight (ESI-TO F) mass spectroscopies. Both phosphoramidite and phosphotriester derivative s of this nucleoside were also prepared as synthetic precursors for DNA oli gomer syntheses.