Risk factor analysis for breast cellulitis complicating breast conservation therapy

Women who undergo breast conservation therapy for early-stage breast cancer can develop breast cellulitis, a complication for which risk factors are u ndefined. A matched case-control investigation was conducted to identify ri sk factors for the development of breast cellulitis among patients who have undergone breast conservation therapy. Patients comprised 17 patients with cases of breast cellulitis diagnosed after partial mastectomies that had b een performed from 1992 through 1997 and 34 control patients who were match ed to case-patients by date of breast lumpectomy and by primary surgeon. St atistical analyses indicated the following factors were associated with bre ast cellulitis: drainage of a hematoma (P = .010); postoperative ecchymosis (P = .021); lymphedema (odds ratio [OR], 10.154; 95% confidence interval [ CI, 1.348-208.860); resected breast tissue volume (OR, 1.456; 95% CI, 1.035 -2.168); and previous number of breast seroma aspirations (OR, 3.445; 95% C I, 1.036-19.771), This is the first matched case-control study to identify risk factors for the development of breast cellulitis after breast conserva tion therapy.