SYNTHESIS AND BIOLOGICAL SCREENING OF SOME NEW 2-PYRAZOLINES, CYANOPYRIDINES AND BENZODIAZEPINES

Citation
Ds. Mehta et al., SYNTHESIS AND BIOLOGICAL SCREENING OF SOME NEW 2-PYRAZOLINES, CYANOPYRIDINES AND BENZODIAZEPINES, Indian Journal of Heterocyclic Chemistry, 6(4), 1997, pp. 271-276
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
09711627
Volume
6
Issue
4
Year of publication
1997
Pages
271 - 276
Database
ISI
SICI code
0971-1627(1997)6:4<271:SABSOS>2.0.ZU;2-N
Abstract
Several new 2-(gamma-picolinoyl amino azo)-ethylacetoacetate (1), amma -picolinoylaminoazo)-3-alylidene-propan-2-ones (2a-j), oylaminoazometh yl)-5-aryl-1-H/acetyl-2-pyrazolines (3a-j), (4a-j), -aryl-6-(gamma-pic olinoylaminoazomethyl)-pyridines (5a-j) and 2-(gamma-picolinoylaminoaz omethyl)-benzodiazepines (6a-j) have been synthesised and screened for their antimicrobial activity. The products 2-6 displayed moderate to good activity. The structures of the products have been elucidated by IR, PMR and mass spectral study.