SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF PHENYLINDOL-3'-YL)METHYLENE]IMIDAZOLIN-5-(4H)-ONES

Authors
PATIL R BIRADAR JS HIREMATH SP MANJUNATH SY
Citation
R. Patil et al., SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF PHENYLINDOL-3'-YL)METHYLENE]IMIDAZOLIN-5-(4H)-ONES, Indian Journal of Heterocyclic Chemistry, 6(4), 1997, pp. 277-280
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian Journal of Heterocyclic Chemistry → ACNP
ISSN journal
09711627
Volume
6
Issue
4
Year of publication
1997
Pages
277 - 280
Database
ISI
SICI code
0971-1627(1997)6:4<277:SAAAOP>2.0.ZU;2-7
Abstract
Twenty one new bstituted-4-[(5'-substituted-2'-phenylindol-3'-yl) meth ylene] imidazolin-5-(4H)-ones (3a-b) were synthesised from the respect ive bstituted-4-[(5'-substituted-2'-phenylindol-3'-yl) methylene] oxoz olin-5-(4H)-ones (2a-c) and appropriate primary amines. 2a-c were obta ined from the 5-substituted-2-phenylindole-3-carboxaldehydes (la-c) an d N-acetylglycine under thermal reaction conditions with acetic anhydr ide and anhyd sodium acetate. The compounds were screened for their an tibacterial activity.