Neutropenia is an uncommon adverse effect associated with prolonged vancomy
cin therapy. Neutrophil counts normally recover after discontinuation of va
ncomycin in this situation, but treatment options are needed for those pati
ents who require ongoing antibiotic therapy. We describe a case of vancomyc
in-induced neutropenia in which the neutropenia resolved after vancomycin w
as replaced by the structurally related compound teicoplanin.