Sn. Pandeya et al., SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF N-MANNICH BASES OF 3-[4-SULPHADIAZINYL]-ISATIN AND DERIVATIVES, Indian Journal of Heterocyclic Chemistry, 6(4), 1997, pp. 313-316
Isatins (1) have been condensed with sulfadiazine (2) to yield 3-sulfa
diazinyisatins (3). Mannich condensation on 3 in presence of CH2O and
secondary amines furnished 3-aminomethyl analogs (4) which were evalua
ted as antimicrobical agents.