SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF N-MANNICH BASES OF 3-[4-SULPHADIAZINYL]-ISATIN AND DERIVATIVES

Citation
Sn. Pandeya et al., SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF N-MANNICH BASES OF 3-[4-SULPHADIAZINYL]-ISATIN AND DERIVATIVES, Indian Journal of Heterocyclic Chemistry, 6(4), 1997, pp. 313-316
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
09711627
Volume
6
Issue
4
Year of publication
1997
Pages
313 - 316
Database
ISI
SICI code
0971-1627(1997)6:4<313:SAAAON>2.0.ZU;2-Y
Abstract
Isatins (1) have been condensed with sulfadiazine (2) to yield 3-sulfa diazinyisatins (3). Mannich condensation on 3 in presence of CH2O and secondary amines furnished 3-aminomethyl analogs (4) which were evalua ted as antimicrobical agents.