Epidemiology, prevention, and early detection of breast cancer

Citation
Aj. Alberg et al., Epidemiology, prevention, and early detection of breast cancer, CURR OPIN O, 12(6), 2000, pp. 515-520
Citations number
59
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
CURRENT OPINION IN ONCOLOGY
ISSN journal
10408746 → ACNP
Volume
12
Issue
6
Year of publication
2000
Pages
515 - 520
Database
ISI
SICI code
1040-8746(200011)12:6<515:EPAEDO>2.0.ZU;2-E
Abstract
Decreases in the incidence of breast cancer have not been achieved, but the re is a downward trend in age-adjusted breast cancer mortality rates in the United States. Recent epidemiologic investigations continue to refine our understanding of the role of established breast cancer risk factors, such a s reproductive characteristics and body mass index, and in the process adva nce understanding of the etiology of breast cancer. Important strides are b eing made in the chemoprevention of breast cancer, but clarifying the poten tial contributions of factors such as diet, physical activity, and cigarett e smoke to the breast cancer burden is a high priority because these lifest yle behaviors also have important implications for primary prevention, The role of both environmental and endogenous exposures in breast carcinogenesi s will be more clearly elucidated by studies that account for genetic polym orphisms, some of which may lead to differential susceptibility to harmful agents. Curr Opin Oncol 2000, 12:515-520 (C) 2000 Lippincott Williams & Wil kins, Inc.