Diabetic patients are four times more likely to develop peripheral vascular
disease than the general population. This disease is likely to be more agg
ressive, with five times more patients developing critical limb ischaemia.
Early diagnosis and treatment allows up to 80% of these patients to have so
me form of surgical or endovascular re-vascularisation. The primary imaging
modalities to be used should be duplex ultrasound followed by angiography.
Magnetic resonance angiography, however, holds out promise for the future
as being a good method of non-invasive imaging. Endovascular (interventiona
l radiological) procedures have a major role to play in treatment of vascul
ar stenoses and occlusions. Thrombolytic agents can be used to dissolve thr
ombus within occluded vessels and so restore patency. Percutaneous translum
inal angioplasty is of value in dilating the stenotic lesions within the ve
ssels and so restoring normal blood flow. Endovascular stents may be insert
ed to ensure longer term patency.
There is indirect evidence to suggest that the outcomes of endovascular pro
cedures in the diabetic patient are less good than those in the general pop
ulation, but nevertheless such procedures may save the diabetic patient fro
m primary amputation and allow healing of ischaemic ulcers. Copyright (C) 2
000 John Wiley & Sons, Ltd.