A prospective study was conducted to measure anxiety and depression in Iran
ian breast cancer patients before and after diagnosis using the Hospital An
xiety and Depression Scale (HADS). The HADS was administered at two points
in time: before diagnosis and 3 months after. In all, 168 breast cancer pat
ients were interviewed. While 48% of patients had severe symptoms of anxiet
y at both baseline and follow-up, more than 60% of patients had no symptoms
of depressive illness at pre-and post-diagnosis assessments. Comparing anx
iety and depression before diagnosis and after 3 months, there were no sign
ificant differences between patients' scores on anxiety (P = 0.42) and depr
ession (P = 0.98) subscales. The results showed that patients with advanced
disease and a lower performance status were more anxious and experienced m
ore depression. The study findings suggest that severe symptoms of anxiety
are the most frequent symptoms in Iranian breast cancer patients. It seems
that during the process of diagnosis and 3 months after psychological morbi
dity persists in patients who suffer from breast cancer.