On the novel cembranoids of the soft coral Sinularia granosa of the IndianOcean and their biogenesis

Authors
Anjaneyulu, ASR Venugopal, MJRV Sarada, P
Citation
Asr. Anjaneyulu et al., On the novel cembranoids of the soft coral Sinularia granosa of the IndianOcean and their biogenesis, I J CHEM B, 39(7), 2000, pp. 530-535
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
39
Issue
7
Year of publication
2000
Pages
530 - 535
Database
ISI
SICI code
0376-4699(200007)39:7<530:OTNCOT>2.0.ZU;2-4
Abstract
Chemical examination of the soft coral Sinularia granosa collected from the Havelock island of the Indian Ocean furnishes four highly oxygenated novel diterpenoids 1 to 4 along with a polyhydroxysterol, 24-methylenecholestane - 1 alpha, 5 alpha, 6 beta, 11 alpha -pentol 5. One of the diterpenoids, 4 , designated as havellockate, possesses a seco and rearranged cembranoid sk eleton whose structure has been established by complete spectral analysis i ncluding X-ray data. A possible biogenetic sequence has been suggested for the polyoxygenated cembranoids 1-4 and 6.