A 51-year-old Japanese man with Churg-Strauss Syndrome (CSS) diagnosed by p
leural biopsy is described. He was hospitalized because of high fever and b
ilateral knee, elbow and shoulder joint pain. Chest roentgenogram and chest
computed tomography (CT) scan revealed bilateral massive pleural effusion.
Pleural biopsy revealed eosinophilic infiltration and necrotizing granulom
as. He was treated with oral prednisolone and his symptoms improved. This i
s the first report of CSS diagnosed by pleural biopsy.