Functional visual explorations of Bardet-Biedl syndrome: a study of three cases

Laurence-Moon syndrome, which is very rare, and Bardet-Biedl syndrome, whic h is more frequent are now well-recognized as two distinct entities in pedi atric neurology. Bardet-Biedi syndrome includes a number of common clinical signs it shares with Laurence-Moon syndrome but also with other syndromes, particularly Alstrome syndrome. These signs are retinitis pigmentosa, ment al retardation, obesity, and hypogonadism. Ophthalmological and electrophys iological examinations are essential for confirmation and correct diagnosis of Bardet-Biedl syndrome. We present three case histories. Our third case illustrates the possibility of below normal yet discernable electroretinogr am amplitudes which do not infirm the diagnosis of Bardet-Biedl syndrome.