Cholic acid is accumulated spontaneously, driven by membrane Delta pH, in many lactobacilli

Authors
Kurdi, P van Veen, HW Tanaka, H Mierau, I Konings, WN Tannock, GW Tomita, F Yokota, A
Citation
P. Kurdi et al., Cholic acid is accumulated spontaneously, driven by membrane Delta pH, in many lactobacilli, J BACT, 182(22), 2000, pp. 6525-6528
Citations number
14
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
182
Issue
22
Year of publication
2000
Pages
6525 - 6528
Database
ISI
SICI code
0021-9193(200011)182:22<6525:CAIASD>2.0.ZU;2-E
Abstract
Many lactobacilli from various origins were found to apparently lack cholic acid extrusion activity. Cholic acid was accumulated spontaneously, driven by the transmembrane proton gradient. Accumulation is a newly identified k ind of interaction between intestinal microbes and unconjugated bile acids and is different from extrusion and modification, which have been described previously.