Synthesis of melithasterol A, a 5 alpha,6 alpha-epoxy-7 alpha-hydroxy Delta(8)-steroid

Authors
Ramesh, P Reddy, VLN Reddy, NS Venkateswarlu, Y
Citation
P. Ramesh et al., Synthesis of melithasterol A, a 5 alpha,6 alpha-epoxy-7 alpha-hydroxy Delta(8)-steroid, J NAT PROD, 63(10), 2000, pp. 1420-1421
Citations number
11
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
10
Year of publication
2000
Pages
1420 - 1421
Database
ISI
SICI code
0163-3864(200010)63:10<1420:SOMAA5>2.0.ZU;2-D
Abstract
A short, first synthesis of melithasterol A (3) utilizing microwave irradia tion-induced isomerization of 5 alpha ,8 alpha -epidioxy steroid (1) as the key step has been achieved in 80% yield.