Citation
Sf. Brady et J. Clardy, CR377, a new pentaketide antifungal agent isolated from an endophytic fungus, J NAT PROD, 63(10), 2000, pp. 1447-1448
Citations number
15
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864
→ ACNP
Volume
63
Issue
10
Year of publication
2000
Pages
1447 - 1448
Database
ISI
SICI code
0163-3864(200010)63:10<1447:CANPAA>2.0.ZU;2-Y
Abstract
Cultures of endophytic fungi collected in the Guanacaste Conservation Area
of Costa Rica were screened for antifungal activity. CR377, a new pentaketi
de antifungal agent, was isolated from the culture broth of a fungus, CR377
(Fusarium sp.), that showed potent activity against Candida albicans in th
is assay. The structure of CR377 was established using 1- and 2-D NMR and H
RFABMS.