The objective of this study was to examine the association between psychiat
ric symptoms and methamphetamine dependence. A four-hour survey was adminis
tered to 1,580 arrestees sampled from the 14 most populous counties in Cali
fornia. The survey included items assessing demographic profile, history of
substance dependence, and psychiatric symptomatology. In the 12 months pri
or to the assessment, methamphetamine-dependent individuals were more likel
y to report depressive symptoms and suicidal ideation than individuals deny
ing methamphetamine dependence, even after controlling for demographic prof
ile and dependence on other drugs, Methamphetamine-dependent individuals al
so weve move likely to report a need for psychiatric assistance at the time
of the interview. These findings suggest that methamphetamine-dependent in
dividuals are at greater risk to experience particular psychiatric symptoms
. Further study to determine the etiology of these symptoms is warranted.