Expression and localization of prohormone convertase 1/3 (SPC3) in porcineovary

Authors
Renegar, RH Owens, CR Dai, GL McMurtry, JP Kwok, SCM
Citation
Rh. Renegar et al., Expression and localization of prohormone convertase 1/3 (SPC3) in porcineovary, MOL REPROD, 57(4), 2000, pp. 361-365
Citations number
30
Categorie Soggetti
Cell & Developmental Biology
Journal title
MOLECULAR REPRODUCTION AND DEVELOPMENT
ISSN journal
1040452X → ACNP
Volume
57
Issue
4
Year of publication
2000
Pages
361 - 365
Database
ISI
SICI code
1040-452X(200012)57:4<361:EALOPC>2.0.ZU;2-8
Abstract
Tissue distribution and cellular localization of PC1/3 mRNA in porcine tiss ues were examined by ribonuclease protection assay and in situ hybridizatio n. PC1/3 mRNA was detected mainly in the corpus luteum of pregnant sow and brain. Within the ovary, PC1/3 and relaxin transcripts colocalized within l arge luteal cells. Levels of PC1/3 transcripts in corpora lutea increased a s gestation advanced, parallel with an observed increase in relaxin transcr ipts. A role for PC1/3 in proprotein processing in the ovary is discussed. (C) 2000 Wiley-Liss, Inc.