Background: Cervical adenocarcinoma and genitourinary malformations are rel
atively common disorders, yet their coexistence is rare.
Case: A 49-year-old woman developed clear cell adenocarcinoma in the atreti
c hemicervix of a communicating uterus type 7 and had ipsilateral renal a,a
genesis. Compared with the unaffected right hemicervix, only the tumor-invo
lved glands of the atretic left hemicervix contained ciliated tuboendometri
al cells. Pour and a half years after radical hysterectomy and pelvic radia
tion, she showed no evidence of recurrence.
Conclusion: In contrast to current opinion, communicating uteri type 7 are
associated with ipsilateral renal agenesis. Our histologic findings support
the hypothesis that tuboendometrial cells are the cells of origin for cerv
ical dear-cell adenocarcinoma (Obstet Gynecol 2000;96:834-6. (C) 2000 by Th
e American College of Obstetricians and Gynecologists.).