Sedation is a clinically important therapeutic intervention in the imminent
ly dying patient. As the patient with an advanced, irreversible illness nea
rs the end of life, symptoms accumulate that are progressively more difficu
lt to manage and that may become refractory to standard medical interventio
ns, The most common of these intractable symptoms are pain, agitated deliri
um, dyspnea and existential or psychological distress. Various therapeutic
options available for relieving these symptoms include physician-assisted s
uicide, euthanasia, acceptance of unrelieved suffering, and terminal sedati
on, Some commentators have voiced concerns that sedating the imminently dyi
ng patient inevitably hastens death, and that this practice, in fact, is a
surrogate form of physician-assisted suicide or euthanasia. Ethical argumen
ts invoked to support the use of terminal sedation include the principle of
double effect, which draws a moral distinction between the intention of an
act(in this case, to relieve suffering) and its foreseen but unintended co
nsequence (premature death). This author views sedation as a necessary, alt
hough risk-laden, procedure that, if practiced by trained, dedicated clinic
ians, maintains the physician's twin obligations to benefit patients and to
"do no harm".