Highly regioselective and stereoselective allylation of aldehydes via palladium-catalyzed in situ hydrostannylation of allenes

Authors
Chang, HM Cheng, CH
Citation
Hm. Chang et Ch. Cheng, Highly regioselective and stereoselective allylation of aldehydes via palladium-catalyzed in situ hydrostannylation of allenes, ORG LETT, 2(22), 2000, pp. 3439-3442
Citations number
36
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
22
Year of publication
2000
Pages
3439 - 3442
Database
ISI
SICI code
1523-7060(20001102)2:22<3439:HRASAO>2.0.ZU;2-4
Abstract
[GRAPHICS] Highly regio and stereoselective allylation of aldehydes by allenes proceed s smoothly in aqueous/organic media in the presence of PdCl2-(PPh3)(2), HCl , and SnCl2. The reaction likely occurs via hydrostannylation of allenes an d allylation of aldehydes by the in situ generated allyltrichlorotins to af ford the final products.