The history of minimally invasive lumbar spine surgery began in 1963 w
ith the introduction of chemonucleolysis. Like this technique, the lat
er development of mechanical nucleotomy and lasernucleotomy aimed prim
arily at reduction of the disc pressure. Miniature optical systems off
ered the opportunity for more specific decompression by discoscopy or,
more recently, by transforaminal epiduroscopy. Initially, nucleotomy
was the only feasible minimally invasive procedure. In recent years, h
owever, minimally invasive spinal fusion became possible due to the de
velopment of new devices (Cages) and advanced transperitoneal (laparos
copic) and retroperitoneal approaches.