Patients that are artificially ventilated via tracheostomy may need heating
and humidification of inspired gas. Neat and moisture exchangers (HME) are
widely used in domiciliary ventilation and manufacturers recommend changin
g them every 24 hours without any scientific evidence. We have reviewed exi
sting evidence which shows that 48 h total use of HME does not increase res
istance to airflow and is not associated with increased incidence of infect
ion. However the efficiency of humidification varies according to HME: Hydr
ophobic units give inadequate humidification and should be changed after 24
h of use. Hygroscopic HME are variable and only those giving an absolute h
umidity of 25 to 30 mg H2O/L should be used for more than 24 h. Condensatio
n in the flex-tube is significantly correlated with values for absolute hum
idity and this may help to evaluate the efficiency of HME.