Effects of N-phosphoproline on the phospholipid of human erythrocytes membrane

The effects of phosphorylated proline on the packing and conformation of th e membrane phospholipid have been studied. Generally it causes the polar pa rts of the phospholipid to become more mobile, the packing of the long chai n of phospholipid to become more loose, the long chain to be in a lower tra ns/gauche ratio, and the end of the long chain to become more orderly. Any change in the level of phosphorylated proline affects the fluidity of the m embrane phospholipid. Free proline and phosphorylated proline have differen t effects on the aliphatic chains of phospholipid.