Intramolecular Mitsunobu reaction in the regio- and stereoselective synthesis of cis-4,5-disubstituted piperidin-2-ones

Authors
Langlois, N Calvez, O
Citation
N. Langlois et O. Calvez, Intramolecular Mitsunobu reaction in the regio- and stereoselective synthesis of cis-4,5-disubstituted piperidin-2-ones, TETRAHEDR L, 41(43), 2000, pp. 8285-8288
Citations number
30
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
43
Year of publication
2000
Pages
8285 - 8288
Database
ISI
SICI code
0040-4039(20001021)41:43<8285:IMRITR>2.0.ZU;2-Z
Abstract
Enantiopure cis-4,5-disubstituted piperidin-2-ones were synthesized through the cyclization of O-benzyl hydroxamates under Mitsunobu conditions, follo wed by samarium diiodide reduction. (C) 2000 Elsevier Science Ltd. All righ ts reserved.