Synthetic study of aquayamycin. Part 2. Synthesis of the AB ring fragment

Authors
Yamaguchi, H Konegawa, T Tanabe, M Nakamura, T Matsumoto, T Suzuki, K
Citation
H. Yamaguchi et al., Synthetic study of aquayamycin. Part 2. Synthesis of the AB ring fragment, TETRAHEDR L, 41(43), 2000, pp. 8389-8392
Citations number
9
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
43
Year of publication
2000
Pages
8389 - 8392
Database
ISI
SICI code
0040-4039(20001021)41:43<8389:SSOAP2>2.0.ZU;2-Y
Abstract
A highly oxygen-functionalized cyclohexenone 2, the AB ring fragment for th e aquayamycin synthesis, was efficiently synthesized via stereoselective ad dition of allylzinc bromide to ketone 3a which, in turn, was available from the optically pure cyclohexane 1,2,3-triol derivative 5. (C) 2000 Elsevier Science Ltd. All rights reserved.