SuperQuat, (S)-4-benzyl-5,5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of alpha-substituted aldehydes

Authors
Bull, SD Davies, SG Nicholson, RL Sanganee, HJ Smith, AD
Citation
Sd. Bull et al., SuperQuat, (S)-4-benzyl-5,5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of alpha-substituted aldehydes, TETRAHEDR-A, 11(17), 2000, pp. 3475-3479
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
17
Year of publication
2000
Pages
3475 - 3479
Database
ISI
SICI code
0957-4166(20000908)11:17<3475:S(FTAS>2.0.ZU;2-4
Abstract
Reduction of alpha -substituted-(S)-N-acyl-4-benzyl-5,5-dimethyl-oxazolidin -2-ones with DIBAL-H in CH2Cl2 affords alpha -substituted aldehydes with no loss of stereochemical integrity at their alpha -centre. (C) 2000 Elsevier Science Ltd. All rights reserved.