Strategy for selective one - Pot aromatization of three different alkynes by organometallic compounds

This paper describes how benzene derivatives were formed with high selectiv ity in one - pot from three different alkynes in excellent yields. Firstly, a novel method for pair - selective coupling of an alkyne with ethylene fo rming zirconacyclopentenes was developed; then, highly selective cross - co upling of two different alkynes forming zirconacyclopentadienes was achieve d; finally, transmetallation of Zr - C bonds to Cu - C bonds in the presenc e of a third alkyne led to the formation of benzene derivatives of three di fferent alkynes. New evidences were obtained for understanding the reaction mechanism.