Ultrasound-guided transthoracic co-axial biopsy of thoracic mass lesions

Purpose: To compare the diagnostic yield of fine-needle aspiration biopsy ( FNAB) and cutting needle biopsy in thoracic lesions. Material and Methods: Thirty patients with thoracic mass lesions were subje cted to ultrasound-guided co-axial FNAB and cutting needle biopsy using 0.7 -mm aspirating and 1.0-mm cutting needles, respectively. The diagnostic yie ld of the individual modalities was compared with the combined yield. Results: A conclusive diagnosis was obtained in 76.6% (n=23) of patients by FNAB and in 66.6% (n=20) by cutting needle biopsy. The combined diagnostic yield of FNAB and cutting needle biopsy was 93.3% (n=28) with a significan t statistical difference (p<0.03) as compared to cutting biopsy alone. Of t he patients, 23.2% (n=7) had benign and 76.6% (n=23) malignant aetiologies. The diagnostic yield of FNAB versus cutting needle biopsy in benign lesion s was 57.1% (n=4) and 100% (n=7), respectively. The diagnostic yield of FNA B versus cutting needle biopsy in malignant lesions was 82.6% (n=19) and 56 .5% (n=13). Two patients remained undiagnosed by either modality. There wer e no complications. Conclusion: FNAB and cutting needle biopsy are complementary to each other and attempts should be made to obtain small tissue cores in addition to rou tine cytologic specimens in diagnosing thoracic lesions, especially in beni gn pathologies. US provides a safe guidance modality for lesions abutting t he chest wall.