Circadian rhythm of serum total homocysteine in men

Authors
Bremner, WF Holmes, EW Kanabrocki, EL Hermida, RC Ayala, D Garbincius, J Third, JLHC Ryan, MD Johnson, M Foley, S Shirazi, P Nemchausky, BA Scheving, LE
Citation
Wf. Bremner et al., Circadian rhythm of serum total homocysteine in men, AM J CARD, 86(10), 2000, pp. 1153
Citations number
21
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
86
Issue
10
Year of publication
2000
Database
ISI
SICI code
0002-9149(20001115)86:10<1153:CROSTH>2.0.ZU;2-M
Abstract
Serum homocysteine levels were examined in a 24-hour study of 7 healthy and 5 diabetic men, revealing a statistically significant circadian rhythm (p = 0.030), normal concentrations of 11.83 1.2 vs 12.99 +/- 1.2 mu mol/L, wit h peak values occurring during the evening (10:37 P.M.) and lowest levels o ccurring during the morning. These findings imply that increased atheroscle rotic risk in insulin-resistant diabetics during morning hours does not app ear to be explained by differences in homocysteine levels in the normal pop ulation.