Calciphylaxis is a complication caused by secondary hyperparathyroidism in
patients with chronic renal failure. These patients may present with clinic
al findings of ischemic necrosis involving: the skin and muscle resulting i
n subsequent gangrene and vascular calcifications. We report a rare case of
necrotizing mastopathy caused by calciphylaxis in a 70-year-old female wit
h end-stage renal disease whose symptoms resolved with a total parathyroide
ctomy.