K. Wahlstrom et al., Trauma in cirrhotics: Survival and hospital sequelae in patients requiringabdominal exploration, AM SURG, 66(11), 2000, pp. 1071-1076
Hepatic cirrhosis significantly increases the mortality and morbidity of el
ective surgery; therefore we hypothesized that cirrhosis would adversely im
pact outcome after abdominal trauma. We used the trauma registry to identif
y 17 patients with cirrhosis who sustained trauma injuries requiring emerge
nt exploratory laparotomy, Patients were characterized with respect to age,
sex, hospital days, intensive care unit days, and trauma scores. A control
group (n = 73) was constructed from the registry by matching age, sex, Inj
ury Severity Score (ISS) and Abbreviated Injury score. Mortality rates were
compared by Fisher's exact test and age, ISS, Revised Trauma Score 2, and
hospital and intensive care unit days were compared by Student's t test. De
spite similar ISS between cirrhotic patients and controls, patients with ci
rrhosis had a fourfold increase in mortality (mortality odds ratio = 7.2; 9
5% confidence interval = 2.2-24.0). Cirrhotic trauma patients had a complic
ation rate of 71 per cent and a mortality of 44 per cent. We conclude that
cirrhosis is a major independent risk factor for mortality in trauma patien
ts with injuries that require emergent abdominal surgery.