Internal standard quantitative method of tetrodotoxin by capillary electrophoresis

Authors
Ru, QH Luo, GA
Citation
Qh. Ru et Ga. Luo, Internal standard quantitative method of tetrodotoxin by capillary electrophoresis, ANAL LETTER, 33(14), 2000, pp. 3013-3023
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL LETTERS
ISSN journal
00032719 → ACNP
Volume
33
Issue
14
Year of publication
2000
Pages
3013 - 3023
Database
ISI
SICI code
0003-2719(2000)33:14<3013:ISQMOT>2.0.ZU;2-F
Abstract
An internal standard quantitative method of tetrodotoxin by capillary elect rophoresis was developed, ephedrine hydrochloride being chosen as the inter nal standard of tetrodotoxin. The calibration curve was built with the cell -elation coefficient of 0.9997, and the linear range was from 0.01 mg.ml(-1 ) to 10.0 mg.ml(-1) with the detection limit of 1.0 x 10(-3) mg.ml(-1). RSD of the migration time of ephedrine hydrochloride and tehrodotoxin were all less than 1.0 %. The method was applied to determine tetrodotoxin in the p oisonous frilled fish samples.