E. Pasquini et al., Breast involvement in immunolymphoproliferative disorders: Report of two cases of multiple myeloma of the breast, ANN ONCOL, 11(10), 2000, pp. 1353-1359
Breast involvement by immunolymphoproliferative disorders is rare. Primary
and secondary malignant lymphomas of the breast are much more common than m
ultiple myeloma, of which only 16 cases have been described. We report two
cases of patients with an established diagnosis of multiple myeloma in whom
breast involvement appeared during the course of the disease. We underline
diagnostic difficulties caused by the lack of clinical and radiological fe
atures which allow us to differentiate between breast carcinoma and breast
involvement by lymphoproliferative disease. Only fine needle aspiration and
/or excisional biopsy can differentiate between immunolymphoproliferative d
isorders and epithelial or mesenchymal tumors of the breast.