Vitamin E modified cellulose membrane

Citation
M. Sasaki et al., Vitamin E modified cellulose membrane, ARTIF ORGAN, 24(10), 2000, pp. 779-789
Citations number
27
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
ARTIFICIAL ORGANS
ISSN journal
0160564X → ACNP
Volume
24
Issue
10
Year of publication
2000
Pages
779 - 789
Database
ISI
SICI code
0160-564X(200010)24:10<779:VEMCM>2.0.ZU;2-#
Abstract
There has been a demand for hemodialysis membranes of better biocompatibili ty, the use of which would reduce the incidence of complications in patient s who have been under long hemodialysis treatment. We developed a surface m odification technique consisting of forming efficiently a synthetic polymer layer on the inside of the regenerated cellulose hollow fiber without impa iring fiber performance. Our newly developed membrane has excellent biocomp atibility by modifying the inner surface and by immobilizing vitamin E (alp ha -tocopherol), which serves as an antioxidant, to the modified surface.