Time dependent changes of subclinical and clinical lameness were analysed i
n 493 fattening bulls in three different herds with a total number of 30.62
1 animals. In the majority of cases subclinical lameness were observed whic
h were caused by metabolic acidosis or deficiencies in mineral intake (P an
d probably Ca). The activity of alkaline phosphatase in plasma exhibited an
increase and the dry matter in bone (tubera coxae) a decrease before the a
ppearance of clinical symptoms. Changes in bone composition were accompanie
d by alterations of plasma Ca and P concentrations, which finally led to cl
inical lameness. Hence the diagnosis was verified by simple laboratory meth
ods as the precondition for successful treatment and prophylaxis of lamenes
s caused by metabolic disorders.