Intermittent maltose feeding enhances paclitaxel production in suspension culture of Taxus chinensis cells

Authors
Choi, HK Kim, SI Son, JS Hong, SS Lee, HS Chung, IS Lee, HJ
Citation
Hk. Choi et al., Intermittent maltose feeding enhances paclitaxel production in suspension culture of Taxus chinensis cells, BIOTECH LET, 22(22), 2000, pp. 1793-1796
Citations number
8
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
BIOTECHNOLOGY LETTERS
ISSN journal
01415492 → ACNP
Volume
22
Issue
22
Year of publication
2000
Pages
1793 - 1796
Database
ISI
SICI code
0141-5492(200011)22:22<1793:IMFEPP>2.0.ZU;2-Z
Abstract
High paclitaxel production (26 mg l(-1)) was achieved through the intermitt ent feeding of 3, 1, and 2% (w/v) sucrose at days 0, 7, and 21, respectivel y, to a suspension culture of Taxus chinensis cells. Intermittent feedings of 1 and 2% (w/v) maltose at days 7 and 21, respectively, to the culture in creased the paclitaxel production up to 67 mg l(-1).