Capsaicin hydrolysis by Candida antarctica lipase

Citation
Dr. Duarte et al., Capsaicin hydrolysis by Candida antarctica lipase, BIOTECH LET, 22(22), 2000, pp. 1811-1814
Citations number
18
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
BIOTECHNOLOGY LETTERS
ISSN journal
01415492 → ACNP
Volume
22
Issue
22
Year of publication
2000
Pages
1811 - 1814
Database
ISI
SICI code
0141-5492(200011)22:22<1811:CHBCAL>2.0.ZU;2-7
Abstract
Capsaicin was hydrolysed by lipase B from Candida antarctica into vanillyla mine and 8-methyl-6-trans-nonenoic acid. Conversions of 70% were obtained a fter 72 h at 70 degreesC in water but decreased to only 15% when capsaicin was solubilized in 15% (v/v) ethanol/water after 72 h at 45 degreesC. No ac tivity occurred in chloroform/water mixtures. According to our knowledge, t his is the first report concerning amide hydrolysis by a lipase.