Intracoronary measurement of pulsus alternans

Pulsus alternans is typically found in patients with left ventricular systo lic dysfunction. We describe a woman with biventricular systolic dysfunctio n and pulsus alternans in the right ventricle, pulmonary artery, and aorta. Coronary angiography revealed an intermediate stenosis in the proximal lef t anterior descending (LAD) coronary artery. Pulsus alternans was demonstra ted in the mid LAD using a 0.014" guidewire-mounted pressure sensor. An abn ormal fractional flow reserve was measured in the LAD. Cathet. Cardiovasc. Intervent. 51:335-338, 2000. (C) 2000 Wiley-Liss, Inc.