Synthesis of benzylcyanoborane adducts of amines and separation of their enantiomers; S(N)2 substitution at boron atom

Authors
Charoy, L Valleix, A Toupet, L Le Gall, T van Chuong, PP Mioskowski, C
Citation
L. Charoy et al., Synthesis of benzylcyanoborane adducts of amines and separation of their enantiomers; S(N)2 substitution at boron atom, CHEM COMMUN, (22), 2000, pp. 2275-2276
Citations number
26
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
22
Year of publication
2000
Pages
2275 - 2276
Database
ISI
SICI code
1359-7345(2000):22<2275:SOBAOA>2.0.ZU;2-0
Abstract
Benzylcyanoborane adducts of several amines were prepared in four steps fro m toluene, their enantiomers were separated using chiral phase HPLC and an S(N)2 pathway was evidenced in the reaction of a trimethylamine-derived ena ntiomer with pyridine.