Effective activation of 'armed' thioglycoside with a new combination of trityl tetrakis(pentafluorophenyl)borate [TrB(C6F5)(4)] and N-(ethylthio)phthalimide (PhthNSEt)

Authors
Jona, H Takeuchi, K Saitoh, T Mukaiyama, T
Citation
H. Jona et al., Effective activation of 'armed' thioglycoside with a new combination of trityl tetrakis(pentafluorophenyl)borate [TrB(C6F5)(4)] and N-(ethylthio)phthalimide (PhthNSEt), CHEM LETT, (10), 2000, pp. 1178-1179
Citations number
12
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
10
Year of publication
2000
Pages
1178 - 1179
Database
ISI
SICI code
0366-7022(20001005):10<1178:EAO'TW>2.0.ZU;2-F
Abstract
Glycosylation of the 'armed' thioglycoside with various glycosyl accepters is promoted by using a combination of stoichiometoric amount of N-(ethylthi o)phthalimide (PhthNSEt) and catalytic amount of trityl tetrakis(pentafluor ophenyl)borate [TrB(C6F5)(4)], and is successfully applied to one-pot 'arme d-disarmed' sequential synthesis of trisaccharides.